As a student at LKSOM in North Philly, I believe each campus has strengths and challenges. If you're looking for advice on the Bethlehem campus, it's a good idea to seek out students at St. Luke's and, for the Temple Health campus, North Philly students. Having spent two years at North Philly, I can only speak to my personal experience here at this campus. I'd refrain from speaking about an experience at a campus I haven't gone to on a typical day-to-day and never went through the application, interview, or matriculation process. Take advice from anyone who does that with a grain of salt. Comparing campuses like that is rarely productive, as each one is unique.
The reality is that these are two different campuses that share a joint mission and benefit from a partnership between both institutions. However, prospective students have to prioritize various aspects when deciding on a campus to apply to. Aspects like having a majority of in-person or virtual lectures as options, student body demographics, class sizes, student-to-professor ratios, surrounding neighborhoods/cities, patient populations, cost of living, proximity to other institutions, and other more important things like proximity to Trader Joe's. Both campuses have advantages and disadvantages, and people may have different preferences for different reasons.
I'd also like to add that the North Philadelphia campus also offers that same "very unique experience" for students to benefit from both the Temple Health and St. Luke's systems through rotations, research, and residencies. All LKSOM students benefit from this partnership, which is not one-sided. However, as you can imagine, students tend to stay at their respective campuses for convenience.