The prescription opioid epidemic in a nutshell

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Brian Tarantina -- who recently played Jackie in Amazon's "The Marvelous Mrs. Maisel" -- died of "acute intoxication by the combined effects of fentanyl, heroin, diazepam and cocaine," the New York City Medical Examiner's office said.

Only because he could no longer find a willing provider?

Addiction is a terrible disease. No mention of his history or Rx.
 
Brian Tarantina -- who recently played Jackie in Amazon's "The Marvelous Mrs. Maisel" -- died of "acute intoxication by the combined effects of fentanyl, heroin, diazepam and cocaine," the New York City Medical Examiner's office said.

Only because he could no longer find a willing provider?

Addiction is a terrible disease. No mention of his history or Rx.
Well, that'll do it.
 
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Primary care doctors do not conduct studies on effectiveness of opioids for chronic pain. They just blindly prescribe whatever the patient asks for.
 
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Mind you, written by a Cardiologist. Probably not prescibing a lot of bzd, but sounds like she or someone close to her is hooked on them.
 


Mind you, written by a Cardiologist. Probably not prescibing a lot of bzd, but sounds like she or someone close to her is hooked on them.
Possibly, but I thought the general consensus was that bzd tapers when done safely took a very long time. The handful I've done took at least 6 months using a protocol I picked up from the NHS several years ago.
 


Mind you, written by a Cardiologist. Probably not prescibing a lot of bzd, but sounds like she or someone close to her is hooked on them.
I read this last night too. My guess is either personal connection or has had to deal with the tachycardia, etc from withdrawal in the hospital multiple times. I also noticed that he didn't mention at all the indications for long term bzo use (few) and glossed over the abuse potential. Just because someone is on benzodiazepines, it does not mean they should be continued.

As with all controlled substances, unless there is an immediate risk, the patient should be tapered off and given meds to ameliorate withdrawal symptoms.
 
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Thoughts? This just passed in Rhode Island.

7 Cancer, palliative care and chronic intractable pain.
8 (a) A practitioner, in good faith and in the course of his or her professional practice
9 managing pain associated with a cancer diagnosis, palliative or nursing home care, intractable or
10 chronic intractable pain as provided in § 5-37.4-2, or other condition allowed by department of
11 health regulations pursuant to the exception in § 21-28-3.20(d), may prescribe, administer, and
12 dispense controlled substances,
or he or she may cause the controlled substances to be
13 administered by a nurse or intern under his or her direction and supervision without regard to the
14 2016 CDC Guideline for Prescribing Opioids for Chronic Pain.

15 (b) Practitioners, in the course of their professional practice, shall not refuse treatment to
16 patients covered under this section for the sole reason that these patients require intensive
17 treatment
 

Attachments

  • Rhode_Island-2020-H7398-Introduced.pdf
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Thoughts? This just passed in Rhode Island.

7 Cancer, palliative care and chronic intractable pain.
8 (a) A practitioner, in good faith and in the course of his or her professional practice
9 managing pain associated with a cancer diagnosis, palliative or nursing home care, intractable or
10 chronic intractable pain as provided in § 5-37.4-2, or other condition allowed by department of
11 health regulations pursuant to the exception in § 21-28-3.20(d), may prescribe, administer, and
12 dispense controlled substances,
or he or she may cause the controlled substances to be
13 administered by a nurse or intern under his or her direction and supervision without regard to the
14 2016 CDC Guideline for Prescribing Opioids for Chronic Pain.

15 (b) Practitioners, in the course of their professional practice, shall not refuse treatment to
16 patients covered under this section for the sole reason that these patients require intensive
17 treatment

Likely to be model legislation to be used in other states.
 
Troubling. End stage cancer and palliative care fine - give them whatever they want. But “chronic intractable pain” covers just about every drug seeker we see. Oh well, I’m not turning them down because of the intensiveness of treatment. I’m turning them down because I don’t prescribe opioids for chronic pain...
 
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Venting......Just had a chronic pain patient I had weaned down from over 500 morphine meq. I had her down to 90 and wanting all the way off. Her pcp just put her back on fentanyl 12mcg patch......... bc she hurts in the middle of the night and gets up to eat and had started gaining weight. Her weight gain started well before wean, and this past 2 months back on fentanyl she is has gained another 2 lbs.... Never. Ending. Battle.
Pain scores have not been consistently different on high doses vs being lowered.
 
Venting......Just had a chronic pain patient I had weaned down from over 500 morphine meq. I had her down to 90 and wanting all the way off. Her pcp just put her back on fentanyl 12mcg patch......... bc she hurts in the middle of the night and gets up to eat and had started gaining weight. Her weight gain started well before wean, and this past 2 months back on fentanyl she is has gained another 2 lbs.... Never. Ending. Battle.
Pain scores have not been consistently different on high doses vs being lowered.
As a PCP, this warrants a call to that PCP
 
Venting......Just had a chronic pain patient I had weaned down from over 500 morphine meq. I had her down to 90 and wanting all the way off. Her pcp just put her back on fentanyl 12mcg patch......... bc she hurts in the middle of the night and gets up to eat and had started gaining weight. Her weight gain started well before wean, and this past 2 months back on fentanyl she is has gained another 2 lbs.... Never. Ending. Battle.
Pain scores have not been consistently different on high doses vs being lowered.

Call to PCP

"Hey man...I'm Dr XXX and I'm the pain physician taking care of XXXXX. I had her down from 500 MED and after all that you threw her back on fentanyl of all things? No offense, but please stay in your lane, and I'll stay in mine. If she is hypertensive in my clinic I won't touch her amlodipine..."
 
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another option: don't bother, tell the patient that the PCP will do all prescriptions and you are done with prescribing, and focus only on procedures, exercises and CBT....

but please, before doing so, give her one last prescription, that of Naloxone Rescue Spray...
 
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Yeah.. that’s the pcps baby now.. you get a script from someone else you are done
 
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Yeah.. that’s the pcps baby now.. you get a script from someone else you are done
I’m surprised the pcp didn’t also tell the patient to get further refills from you, since he can’t write them long term.
But seriously, not your problem anymore
 
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Luckily, patient wants meds from PCP and injections from me.
This PCP is known for sending over cringe worthy referrals. Every single one seemed to be on a benzo, opioid, sleep aid, and stimulant. I don't understand how this is still happening.
 
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We have been remiss on this thread. Time to ramp it again.


The following statement is attributable to:
Patrice Harris, M.D., M.A.
Chair, AMA Opioid Task Force
Immediate Past President, American Medical Association


“The AMA strongly endorses today’s decision by HHS to allow physicians to prescribe without a waiver highly effective medication for the treatment of patients with opioid use disorder. Patients are struggling to find physicians who are authorized to prescribe buprenorphine; the onerous regulations discourage physicians from being certified to prescribe it. The AMA urged HHS to change the regulations last year in order to remove a major barrier to reducing the nationwide epidemic of drug-related overdose and death.

“With this change, office-based physicians and physician-led teams working with patients to manage their other medical conditions can also treat them for their opioid use disorder without being subjected to a separate and burdensome regulatory regime. Ensuring physician-led teams for treating patients with opioid use disorder is critical to ending the opioid epidemic. Removing the waiver requirement can also help lessen the stigma associated with this treatment and the persistent health disparities in treating substance use disorders.

“It is estimated that more than two million Americans need treatment for opioid use disorder, but only a small percentage actually receive treatment. The Centers for Disease Control and Prevention recently reported an acceleration of overdose deaths during the COVID-19 pandemic, which has made accessing care more challenging.”

“Treatment with buprenorphine allows patients with opioid use disorder to lead satisfying, productive lives. The policy announced today is a critically important step in making that happen.”
 

The following statement is attributable to:
Patrice Harris, M.D., M.A.
Chair, AMA Opioid Task Force
Immediate Past President, American Medical Association


“The AMA strongly endorses today’s decision by HHS to allow physicians to prescribe without a waiver highly effective medication for the treatment of patients with opioid use disorder. Patients are struggling to find physicians who are authorized to prescribe buprenorphine; the onerous regulations discourage physicians from being certified to prescribe it. The AMA urged HHS to change the regulations last year in order to remove a major barrier to reducing the nationwide epidemic of drug-related overdose and death.

“With this change, office-based physicians and physician-led teams working with patients to manage their other medical conditions can also treat them for their opioid use disorder without being subjected to a separate and burdensome regulatory regime. Ensuring physician-led teams for treating patients with opioid use disorder is critical to ending the opioid epidemic. Removing the waiver requirement can also help lessen the stigma associated with this treatment and the persistent health disparities in treating substance use disorders.

“It is estimated that more than two million Americans need treatment for opioid use disorder, but only a small percentage actually receive treatment. The Centers for Disease Control and Prevention recently reported an acceleration of overdose deaths during the COVID-19 pandemic, which has made accessing care more challenging.”

“Treatment with buprenorphine allows patients with opioid use disorder to lead satisfying, productive lives. The policy announced today is a critically important step in making that happen.”

If you think back to the mid 1990s and you replace the word buprenorphine with OxyContin, doesn’t this seem like history repeating itself?
 
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The following statement is attributable to:
Patrice Harris, M.D., M.A.
Chair, AMA Opioid Task Force
Immediate Past President, American Medical Association


“The AMA strongly endorses today’s decision by HHS to allow physicians to prescribe without a waiver highly effective medication for the treatment of patients with opioid use disorder. Patients are struggling to find physicians who are authorized to prescribe buprenorphine; the onerous regulations discourage physicians from being certified to prescribe it. The AMA urged HHS to change the regulations last year in order to remove a major barrier to reducing the nationwide epidemic of drug-related overdose and death.

“With this change, office-based physicians and physician-led teams working with patients to manage their other medical conditions can also treat them for their opioid use disorder without being subjected to a separate and burdensome regulatory regime. Ensuring physician-led teams for treating patients with opioid use disorder is critical to ending the opioid epidemic. Removing the waiver requirement can also help lessen the stigma associated with this treatment and the persistent health disparities in treating substance use disorders.

“It is estimated that more than two million Americans need treatment for opioid use disorder, but only a small percentage actually receive treatment. The Centers for Disease Control and Prevention recently reported an acceleration of overdose deaths during the COVID-19 pandemic, which has made accessing care more challenging.”

“Treatment with buprenorphine allows patients with opioid use disorder to lead satisfying, productive lives. The policy announced today is a critically important step in making that happen.”
You assume all patients on opiates have OUD?
 
I have 4 pts I inherited from my predecessor on 90-120 MME. Should I start tapering them down to avoid this 'cherry-pick'-ing, if that is indeed what happened to her?

It sounds like she was treating fibromyalgia. Obvy avoid 120 MED fibro patients
 
I have 4 pts I inherited from my predecessor on 90-120 MME. Should I start tapering them down to avoid this 'cherry-pick'-ing, if that is indeed what happened to her?
no.

you should review each of the cases independently. do your due diligence as if it were a patient you were seeing for the first time.

confirm a definitive diagnosis, one that can be verified on, say MRI scan or lab work. check your urines, look at your PMPs, do UDS, etc. have them sign a new treatment agreement.


----------------------------

with regards to Dr. Basch - an "integrative" family practitioner "specializing in pain management",. there are always 2 sides and these articles are all essentially an advertising blitz by Basch. the truth? here is the official documentation, and they paint a completely different picture.


Patient 1 - Methadone 20 mg three times daily, oxycodone 15 mg every 4 hours as needed (60 mg), Oxycodone 30 mg 1-2 tab up to maximum 6 per day (180 mg), and lorazepam 1-2 mg twice daily
patient had elevated QT interval in 2014. no dose change or follow up EKG. in fact, it was increased then decreased by 10 mg over time, and ultimately went up 10 mg "because P1 admitted to respondent that she had increased her methadone dose on her own by 10 mg". she states that she plans on tapering multiple times through the years, but apparently the notes are "cut and pasted" and "making it very difficult, if not impossible, to know what actions were taken when." "Patient-1 regularly breached her pain medication contract without apparent consequences"

Patient 2 - was hospitalized for severe constipation on fentanyl and hydrocodone, discharged on butrans and tramadol. she took over, never signed treatment agreement, allowed patient to alter her tramadol dose, kept calling butrans "suboxone", and apparently cut and pasted most of her notes, with no clear plan.

Patient 3 - DJD and osteoarthritis, took over patient on dilaudid and tramadol, temazepam and clonazepam and butalbutal. MME at that time 160. she added on fentanyl, so MME went up to 340. treatment agreement signed but had wrong age. patient then noted to miss 2 appointments and staff noted cognitive decline. she told patient to limit clonazepam, patient apparently "shrugged her concern off". Basch did not change prescription - clonazepam 4 times daily... she noted as early as 2014 that the medications don't seem to improve patients pain, but ultimately dosage went from 160 to 424 MED. at one point, there was a switch between fentanyl to OxyContin, but the board doesn't seem to know when that happened. she was also noted to continue to prescribe 2 benzos even though patient admitted to 2 drinks per day and was using alcohol for the pain. again, most of her notes were apparently cut and pasted.

Patient 4 - cervical radic and spondylolisthesis, she took over in 2015 when he was on 960 mg oxycodone per day with 30 mg temazepam. a pain specialist stated patient should be tapered 10% per month until on oxycodone 10 mg 4 times daily and OxyContin 80 mg 3 times daily. guess what - she didn't taper that way. 4 months later, he was down 15% but then she went back up on dosage - to 900 mg oxycodone a day. in 2016, he reported that he was running out because the prescriptions were running late. she noted he was getting 30 day supply every 28 days... but she gave him extra script as a buffer. all while continuing temazepam - and for 3 months increasing temazepam from 30 to 45 mg daily. at one point, she added ambien per the patient request on top of temazepam. med list stated OxyContin 40 mg every 6 to 8 hours as needed and OxyContin 80 mg every 4 hours but pharmacy script was 3 times daily - discrepancy between what is in her notes and the prescription.

ultimately, he did have neck surgery, she did taper him but only got to 630 MED not the 420 MED recommended by the pain specialist...

Patient 5 - well, more of the same. dilaudid 4 mg 6 times daily, oxymorphone 40 mg 6 times daily, 6 mg alprazolam, and 10 mg nortripyline. patient fell, no apparent concern, had bruise in his arm (? concern IVDA) and she did not investigate. he accidentally washed some pills, brought in the washed and partially whole pills. she gave refill script. at one point, the pharmacy gave out full prescription of drug on Feb 15 and again on Feb 21. she requested the pharmacy investigate, they did and confirmed the 2 prescriptions within 7 days, but she believed the patient instead and gave him a tide over prescription for morphine. she also at one point wrote for more pills so he could develop a reservoir in case the pharmacy gave him trouble. she did eventually taper a bit... her notes from initial visits in August 2015 discuss taper, which she finally started in Dec 2017, from MME 816 down to MME of 664....
 
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She is a drug dealer and should be stripped of her license. And go to jail. There is no legit medical care based on the investigation. Having an MD/DO and saying I did not know is not a defense.
 
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I am curious what was the actual "Medical Board of California's policy requiring physicians quickly taper legacy pain patients off opioids" was.

Obviously there is gross medication mismanagement in that office as alluded to by Ducttape's post.
 
no.

you should review each of the cases independently. do your due diligence as if it were a patient you were seeing for the first time.

confirm a definitive diagnosis, one that can be verified on, say MRI scan or lab work. check your urines, look at your PMPs, do UDS, etc. have them sign a new treatment agreement.


----------------------------

with regards to Dr. Basch - an "integrative" family practitioner "specializing in pain management",. there are always 2 sides and these articles are all essentially an advertising blitz by Basch. the truth? here is the official documentation, and they paint a completely different picture.


Patient 1 - Methadone 20 mg three times daily, oxycodone 15 mg every 4 hours as needed (60 mg), Oxycodone 30 mg 1-2 tab up to maximum 6 per day (180 mg), and lorazepam 1-2 mg twice daily
patient had elevated QT interval in 2014. no dose change or follow up EKG. in fact, it was increased then decreased by 10 mg over time, and ultimately went up 10 mg "because P1 admitted to respondent that she had increased her methadone dose on her own by 10 mg". she states that she plans on tapering multiple times through the years, but apparently the notes are "cut and pasted" and "making it very difficult, if not impossible, to know what actions were taken when." "Patient-1 regularly breached her pain medication contract without apparent consequences"

Patient 2 - was hospitalized for severe constipation on fentanyl and hydrocodone, discharged on butrans and tramadol. she took over, never signed treatment agreement, allowed patient to alter her tramadol dose, kept calling butrans "suboxone", and apparently cut and pasted most of her notes, with no clear plan.

Patient 3 - DJD and osteoarthritis, took over patient on dilaudid and tramadol, temazepam and clonazepam and butalbutal. MME at that time 160. she added on fentanyl, so MME went up to 340. treatment agreement signed but had wrong age. patient then noted to miss 2 appointments and staff noted cognitive decline. she told patient to limit clonazepam, patient apparently "shrugged her concern off". Basch did not change prescription - clonazepam 4 times daily... she noted as early as 2014 that the medications don't seem to improve patients pain, but ultimately dosage went from 160 to 424 MED. at one point, there was a switch between fentanyl to OxyContin, but the board doesn't seem to know when that happened. she was also noted to continue to prescribe 2 benzos even though patient admitted to 2 drinks per day and was using alcohol for the pain. again, most of her notes were apparently cut and pasted.

Patient 4 - cervical radic and spondylolisthesis, she took over in 2015 when he was on 960 mg oxycodone per day with 30 mg temazepam. a pain specialist stated patient should be tapered 10% per month until on oxycodone 10 mg 4 times daily and OxyContin 80 mg 3 times daily. guess what - she didn't taper that way. 4 months later, he was down 15% but then she went back up on dosage - to 900 mg oxycodone a day. in 2016, he reported that he was running out because the prescriptions were running late. she noted he was getting 30 day supply every 28 days... but she gave him extra script as a buffer. all while continuing temazepam - and for 3 months increasing temazepam from 30 to 45 mg daily. at one point, she added ambien per the patient request on top of temazepam. med list stated OxyContin 40 mg every 6 to 8 hours as needed and OxyContin 80 mg every 4 hours but pharmacy script was 3 times daily - discrepancy between what is in her notes and the prescription.

ultimately, he did have neck surgery, she did taper him but only got to 630 MED not the 420 MED recommended by the pain specialist...

Patient 5 - well, more of the same. dilaudid 4 mg 6 times daily, oxymorphone 40 mg 6 times daily, 6 mg alprazolam, and 10 mg nortripyline. patient fell, no apparent concern, had bruise in his arm (? concern IVDA) and she did not investigate. he accidentally washed some pills, brought in the washed and partially whole pills. she gave refill script. at one point, the pharmacy gave out full prescription of drug on Feb 15 and again on Feb 21. she requested the pharmacy investigate, they did and confirmed the 2 prescriptions within 7 days, but she believed the patient instead and gave him a tide over prescription for morphine. she also at one point wrote for more pills so he could develop a reservoir in case the pharmacy gave him trouble. she did eventually taper a bit... her notes from initial visits in August 2015 discuss taper, which she finally started in Dec 2017, from MME 816 down to MME of 664....
wow thank you for that summary and for the link...I had not considered the possibility of this other atrocious picture but I will remember it. I do all of the things you suggested above and have good dx for those patients. I coincidentally just had a patient who called with a washed-pills scenario too, but did not give her a replacement script.
 
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I am curious what was the actual "Medical Board of California's policy requiring physicians quickly taper legacy pain patients off opioids" was.

Obviously there is gross medication mismanagement in that office as alluded to by Ducttape's post.
there are multiple comments about this, particularly with Patient 4, where the patient saw the pain management specialist and the taper program was listed in the documentation. she clearly did not follow it, and at one point even went up on the dosage.
 
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Just wow.. amazing any of those patients survived.. or were they all overdoses?
 
no overdoses thankfully.

these cases are signs of how amazingly tolerant humans can become....




which may help explain why my wife hasn't left yet....
 
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Just wow.. amazing any of those patients survived.. or were they all overdoses?

You don’t overdose when you’re selling your pills. Each one of those easily $10–15 a pill...maybe more given cost of living in California
 
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Oh I certainly get the selling the medication thing. When I was in my previous opioid hotspot it was about 1$ per mg oxycodone. So a “roxy 30” was worth 30$. Those getting 4 a day we’re getting 120$ a day or 3600$ per month. That’s not counting the ER and Xanax. However most of these folks tend to develop their own drug problems.. the old one for you one for me deal and many end up on heroin or overdose.
 
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New patient referred and I overhear nurse on phone setting up visit.
Counseling regarding no family or friends in room, no opiates prescribed, bring in outside records/imaging on CD.
For this patient, has nurse tell her that I would not Rx opiates ever for her problems...
Patient says, " Who been talkin?"

Nurse laughs and the entire hallway was cracking up.
 
Senior citizen shows up in my office, no notes from his neurologist but he's been taking hydrocodone and soma for years. Until last week when he took more and more and then had a cardiac arrest and was intubated/hospitalized for 3 days. Now suddenly he has to get his medications from a pain doctor according to this neurologist who has been feeding him for the last 3 years. Zero remorse that he overdosed himself and almost died.
 
If you think back to the mid 1990s and you replace the word buprenorphine with OxyContin, doesn’t this seem like history repeating itself?
Not really. bup is much much safer than oxycontin.

Not risk free either, but much safer.

Personally, I feel that one of the best ways to improve the opioid epidemic is to force every insurance carrier in the country to cover butrans, belbuca, and bup, and to require that in a non-terminal patient, that butrans/belbuca must be tried first and in at least two different doses before any patient can be prescribed any long acting standard opioid.
 
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Not really. bup is much much safer than oxycontin.

Not risk free either, but much safer.

Personally, I feel that one of the best ways to improve the opioid epidemic is to force every insurance carrier in the country to cover butrans, belbuca, and bup, and to require that in a non-terminal patient, that butrans/belbuca must be tried first and in at least two different doses before any patient can be prescribed any long acting standard opioid.
Wasn't Oxycontin safer than Oxycodone IR? I seem to remember hearing about that...
 
Suboxone still has street value. It’s sold to other addicts to keep them “well” in between when they can access heroin. They have no interest in quitting, they just don’t want to feel sick while they’re saving up for the real thing.
 
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