I'm confused by the post above me.
I'm pretty sure Ponce, is considered a USMD Allopathic school. Hence why its in the Allopathic thread of the pre-med forum. Puerto Rico is a US territory, and Puerto Rican born citizens are have US citizenship. I don't think attending Ponce will hurt his/her/they chances at practicing medicine in the US or getting a Residency spot, unlike IMG/FMGs.
I too think this is a "no-brainer" OP's friend should attend Ponce. Ponce already accepted him compared to a CONDITIONAL acceptance after a 1yr MPH, which also means losing out on 1yr of Physician salary, ~$250k. If OP's friend works hard and is really savvy he/she/they could even use the unique experiences brought by attending medical school at Ponce, and the challenges that bring as way to positively bring attention to his residency application.