Tbh, personally I don't think this makes it any less accurate for like 95% of the audio lectures I would say are perfect even for today (the pathophysiology for most things have not changed). However there are a few things that are considered "wrong" in terms of current times, but I think that if you have not been in a coma for the first 2 years of med school, you'll pick these out (e.g. Using troponin I for MI dx and CK MB for reinfarction instead of what Goljan says because troponin test was not as well established back then in literature/journals.).