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[pccm_guy]

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[anonperson]

Does anyone know if a subchorionic hematoma would lower the fetal fraction on NIPT? I read that excess adipocity can do this due to tissue necrosis and inflammation, but can the same be said about a SCH that was small and resolved in the first trimester?

I have not read anything related to a subchorionic hematoma affecting NIPT results.

California has transitioned entirely to NIPT for Downs screening and I don't recall them mentioning anything about subchorionic bleeds affecting results.

Regarding increased "adiposity", 60% of the patient population is obese or overweight. I have not seen any invalid results in my obese patients.