If you really can't move, that's a tough spot to be in, especially with the PSLF issue. My reflexive answer is no but I could barely tolerate the 30 minute commute at my last job, and part of the selection process for my current (and expected-to-be final) job was a commute under 15 minutes.
90 minutes each way is 3 hours of driving each day, or ~15 hours of unpaid time every week. If this $550K & 8 week vacation job is an average 50ish hour/week job, then it's really a 65 hour/week job. 550 / 44 / 65 = $192/hour
It's actually less than that, since your "home call" is going to be spent in a call room, hotel, or a van down by the river. How do you value that time? It's not zero.
If you could commute on good public transit and use that time to read or relax, maybe it'd be tolerable and I wouldn't mentally bill the time to the job.
If you moved closer to that hospital, the stuff you're close to now would only be 90 minutes away. Is there a reason why that "commute" is unthinkable, but the same commute to work isn't?
Or do you have family / spousal-job reasons to be anchored where you're at?